Curriculum Vitae
Jyuhn-Huarng Juang
1. Name: Jyuhn-Huarng Juang
- Degree Completed: MD
- Current Profession & Workplace:
Professor,
Division of Endocrinology and Metabolism,
Chang Gung Memorial Hospital, Taoyuan,
Taiwan, R.O.C.
2. Education:
1975-1982 M.D., Taipei Medical College, Taipei, Taiwan, R.O.C
8/1992-7/1994
Research
Fellow, Section on Islet Transplantation and Cell Biology, Joslin Diabetes
Center,
Boston, Massachusetts, U.S.A. (Prof. Gordon C. Weir)
10/1985-1/1986
Fellow,
Clinical Research Center, Department of Medicine, Stanford University, Palo
Alto,
California, U.S.A. (Prof. Gerald Reaven)
3. Employment History:
7/2009 Professor, Division of Metabolism and Endocrinology, Department of
Internal
Medicine, Chang Gung Memorial
Hospital, Taoyuan, Taiwan, R.O.C.
2/2010–2/2022 Professor, Department of Medicine, College of Medicine, Chang Gung University, Taoyuan, Taiwan, R.O.C.
7/2003 – 6/2006 Chief, Division of Endocrinology and Metabolism, Department of Internal Medicine, Chang Gung Memorial Hospital, Taoyuan, Taiwan, R.O.C.
9/2003 – 11/2005 Chief, Department of Nutrition Therapy, Chang Gung Memorial Hospital, Taoyuan, Taiwan, R.O.C.
7/1996–6/1997 Chief, First Division of Endocrinology and Metabolism, Department of Internal Medicine, Chang Gung Memorial Hospital, Taoyuan, Taiwan, R.O.C.
4. Professional Experiences:
1998-2016 Executive Board, the Diabetes Association of the Republic of China
2002-2011 Executive Board, Taiwanese Association of Diabetes Educators
5. Publication: Selected from 180 referred papers
1. Juang JH et al: Beneficial influence of glycemic control upon the growth and function of transplanted islets. Diabetes 43:1334-9, 1994.
2. Juang JH et al: Outcome of subcutaneous islet transplantation improved by polymer device. Transplantation 61:1557-61, 1996.
3. Lin KD … Juang JH: Metformin-induced hemolysis with jaundice. N Engl J Med 339:1860-1,1998.
4. Juang J-H et al: Influence of donor age on mouse islet characteristics and transplantation. Cell Transplant 10:277-84, 2001.
5. Juang JH et al: Beneficial effects of hyperbaric oxygen therapy on islet transplantation. Cell Transplant 11;95-101, 2002.
6. Sung HH, Juang JH et al: Transgenic expression of decoy receptor 3 protects islets from spontaneous and chemical-induced autoimmune destruction in nonobese diabetic mice. J Exp Med 199:1143-51, 2004.
7. Juang J-H et al: Exendin-4 treatment expands graft b-cell mass in diabetic mice transplanted with a marginal number of fresh islets. Cell Transplant 17:641-7, 2008.
8. Sonajea K … Juang J-H, et al: Biodistribution, pharmacodynamics and pharmacokinetics of insulin analogues in a rat model: Oral delivery using pH-responsive nanoparticles vs. subcutaneous injection. Biomaterials 31:6849-58, 2010.
9. Nguyena H-N … Juang J-H et al: The glucose-lowering potential of exendin-4 orally delivered via a pH-sensitive nanoparticle vehicle and effects on subsequent insulin secretion in vivo. Biomaterials 32:2673-82, 2011.
10. Juang J.-H. et al: Magnetic resonance imaging of mouse islet grafts labeled with novel chitosan-coated superparamagnetic iron oxide nanoparticles. PLoS One 8: e62626, 2013.
11. Chuang EY … Juang JH et al: Combination therapy via oral co-administration of insulin- and exendin-4-loaded nanoparticles to treat type 2 diabetic rats undergoing OGTT. Biomaterials 34:7994-8001, 2013.
12. Juang JH et al: Three-dimensional islet graft histology: panoramic imaging of neural plasticity in sympathetic reinnervation of transplanted islets under the kidney capsule. Am J Physiol Endocrinol Metab 306:E559-E570, 2014.
13. Juang JH et al: 3-D imaging reveals participation of donor islet schwann cells and pericytes in islet transplantation and graft neurovascular regeneration. EBioMedicine 2:109-19, 2015.
14. Chien HJ … Juang JH, Tang SC: 3-D imaging of islets in obesity: formation of the islet-duct complex and neurovascular remodeling in young hyperphagic mice. Int J Obes (Lond) 40:685-97, 2016.
15. Li WC ... Juang JH: Porcine neonatal pancreatic cell clusters maintain their multipotency in culture and after transplantation. Sci Rep 8:8212, 2018.
16. Chuang EY … Juang JH et al: An intestinal "transformers"-like nanocarrier system for enhancing the oral bioavailability of poorly water-soluble drugs. ACS Nano 12:6389-6397, 2018.
17. Yu C-P, Juang J-H et al: Enhancement of subcutaneously transplanted β cell survival using 3D stem cell spheroids with proangiogenic and prosurvival potential. Adv Biosyst 2020;4:e1900254.
18. Juang J-H et al: Noninvasive tracking of mPEG-poly(Ala) hydrogel-embedded MIN6 cells after subcutaneous transplantation in mice. Polymers 2021;13:885.
19. Juang JH et al: Magnetic Resonance imaging of transplanted porcine neonatal pancreatic cell clusters labeled with chitosan-coated superparamagnetic iron oxide nanoparticles in mice. Polymers 2021;13:1238.
20. Juang JH et al: Implanted islet mass influences the effects of dipeptidyl peptidase-IV inhibitor LAF237 on transplantation outcomes in diabetic mice. Biomed J. 2021;44(Suppl 2):S210-S217.
21. Juang J-H et al: Exendin-4-conjugated manganese magnetism-engineered iron oxide nanoparticles as a potential magnetic resonance imaging contrast agent for tracking transplanted β-cells. Nanomaterials 2021; 11:3145.
22. Juang J-H, et al: Magnetic resonance imaging of transplanted porcine neonatal pancreatic cell clusters labeled with exendin-4-conjugated manganese magnetism-engineered iron oxide nanoparticles. Nanomaterials 2022;12:1222.
23. Juang J-H, et al: The Image–Histology Correlation of Subcutaneous mPEG-poly(Ala) Hydrogel-Embedded MIN6 Cell Grafts in Nude Mice. Polymers 2023;15:2584.